Preclinical Imaging Consortium 2025!

We had a fantastic time in Houston last week at the Preclinical Imaging Consortium (PIC) 2025! A big thank you to the amazing SAIF team at MD Anderson Cancer Center for organizing such a valuable event. It was a pleasure to once again share a booth with our partners at Phantech, LLC Medical and connect with researchers about how Imalytics Preclinical can streamline and elevate their imaging workflows. Mark Tchinov also gave a great talk highlighting our latest developments in automation—from robust quality control to AI-driven segmentation and our high-throughput PET/SPECT-CT biodistribution analysis pipeline.
Looking forward to seeing you again next year!

EMIM 2025 (Bilbao)

Gremse-IT had a great time at the European Society for Molecular Imaging - ESMI conference last week, connecting with scientists, industry partners, and researchers pushing the boundaries of molecular imaging.

During our industry session presentation we had the chance to highlight our recent developments and upcoming innovations. Justin Jeffery provided a fascinating look at Phantech, LLC’s journey, from its first phantom designs to its collaborations with us and RadQual. PD Dr. Felix Gremse demonstrated our dosimetry tool and AI-based automated segmentation live, showcasing the power of Imalytics for efficient quantitative imaging research.

Thanks to everyone who joined us, looking forward to continuing these collaborations!

TRP Target Selection & Drug Design

How can machine learning accelerate your image analysis in radiopharmaceutical development? Gremse-IT was at the TRP Target Selection & Drug Design Summit in Boston to find out.
PD Dr. Felix Gremse (CEO) and Zach Gurberg (COO) learnt more about your radiopharmaceutical design and development processes and together we explored how Gremse-IT’s advanced software, automation, and image analysis services can accelerate your preclinical studies. We discussed how our end-to-end automated biodistribution study pipeline and voxel-based dosimetry tool can enhance your efficiency in radiopharmaceutical development.

100+ Tutorial Videos Available!

As we continue to develop our Imalytics Preclinical Software, we are constantly recording and uploading new tutorial videos to support our users. Currently, there are over 100 short and informative tutorial videos accessible directly within Imalytics Preclinical and on our YouTube channel! Whether you're exploring image fusion, fat segmentation, bone analysis, or other advanced tools, these tutorials are designed to help you maximize the potential of our software.

✅ Check out the tutorials now and streamline your imaging workflows!

💡 Have a workflow process you’d like developed into a tutorial video, message us as info@gremse-it.com!

Meet us at the EMIM in Bilbao

We look forward to seeing you at #EMIM 2025 in Bilbao.

Meet us at our booth #208 or come to our industry session on March 13!

Virtual assistant

We recently launched our virtual assistant, designed to help Imalytics Preclinical users navigate our software and answer any image analysis related questions!
This intelligent virtual assistant is built to:
✔️ Quickly answer your questions
✔️ Suggest common workflows
✔️ Help you troubleshoot
✔️ Simplify your experience
As we continue to work on this tool, we welcome your feedback to help shape its development. Your insights will guide us in ensuring the Virtual Assistant works smoothly and suits your needs.
💬 Curious to try it out and share your thoughts? We’re eager to hear what you think!

Publication Highlight 📖🔬

In this innovative study, ImalyticsPreclinical played a crucial role in the characterization of pulmonary pathology in a Golden Syrian hamster model of COVID19. Our software enabled precise manual segmentation of microCT scans to analyze lung abnormalities, including ground-glass opacities (GGOs), consolidations, and pneumomediastinum, providing key insights into disease progression. Congratulations to Shambhunath Choudhary and the team at Pfizer for advancing preclinical modeling of respiratory diseases!

Check out the full article here:

Imalytics Preclinical: Comparison

The new year has just started, and Gremse-IT wishes you a happy new year and good luck with all your preclinical imaging studies. To kick off 2025, we wanted to showcase how Imalytics Preclinical stands apart from in-house developments in this easy-to-read comparison table.
From thoroughly tested solutions to multi-modal analysis, standardized workflows, and more, Imalytics Preclinical offers a robust, reliable, and researcher-focused platform trusted by imaging cores worldwide. Take a look and see how our software is designed to simplify and enhance preclinical imaging research. Interested in learning more? Contact us for a demo at info@gremse-it.com and see how Imalytics Preclinical can support your research!

Grace File Format (GFF)

At Gremse-IT, we’ve created the Grace File Format (GFF) to simplify multimodal imaging data management. GFF is open-source and supports any imaging modality, including CT, PET, SPECT, US, and MRI. This GFF format enables researchers to store multimodal images in a single format while reducing file size with lossless compression, preserving quality. This format also ensures data integrity with cryptographic hashing and optional saving timestamps.

By removing file-format bottlenecks, GFF lets researchers focus on what truly matters: advancing biomedical imaging research.
📩 Questions? Contact us at info@gremse-it.com or explore the GitHub repository here: https://lnkd.in/eUPqHBA7
🔗 Learn more by reading the publication by Grace et al.:

🎅 Christmas holidays 2024 🎅

This holiday season, the Gremse-IT family celebrated across two continents with two great experiences!

Our German team headed to Maastricht, Netherlands, where they explored the historic Fort Sint Pieter, solved puzzles, and wrapped up the day with a stroll through the charming Vrijthof Christmas Market and a cozy dinner.

Meanwhile, our Montreal team gathered for a dinner filled with good food, great conversations, and plenty of holiday cheer.

Although miles apart, the Gremse-IT family came together to celebrate another fantastic year.

Happy Holidays from all of us at Gremse-IT!

Cosmodome de Laval

The holiday season is in the air, and we had the pleasure of attending the Holiday Cocktail hosted by Biotech City and BIOQuebec held at the iconic Cosmodôme de Laval. This was our very first event after officially joining the association this summer and it was great to connect with other innovative companies right here in Québec!

We're thrilled to be part of such a vibrant community and are looking forward to attending more events in the future.

Spotlight on Imalytics: Brain Atlas Tool

We’re excited to highlight one of the most useful features of our Imalytics Preclinical software—the Brain Atlas Tool!
This tool streamlines the process of atlas-based segmentation, offering a quick and easy workflow designed to save you time and effort.

1. Select an Atlas: Choose from a library of atlases designed for different regions of interest.
2. Align Your Image: Rotate and zoom your underlay to align with the selected atlas in all slice views.
3. Generate Segmentation: Within seconds, ou can create a detailed segmentation, tailored to your specific study.

Our Brain Atlas Tool provides the precision and flexibility needed for your analysis, and researchers are also capable of creating their own atlases. Watch the video below to see this tool in action!

Publication Highlight 📖🔬

In this study, ImalyticsPreclinical was used to analyze µCT images of scaffolds implanted in mice. Our software enabled precise evaluation of mineralization and scaffold integration. The collagen sponge displayed significant mineralisation compared to the uncoated PCL scaffolds. Imalytics Preclinical played a key role in processing and analyzing the µCT scans to highlight these differences.
Check out the full article for more details:

🎉 We’ve Hit 500 Followers! 🎉

A heartfelt thank you to each of our 500 followers for joining us on our mission to make biomedical image analysis faster, easier and more reliable! Our growth would not be possible without the incredible support from our partners, clients, and, of course, our dedicated followers. Stay tuned for exciting updates, new features, and innovations as we continue to transform the way researchers approach image analysis.
Thank you for being a part of Gremse-IT’s journey and continued success!

BIOEMTECH meeting (Athens, October 2024)

Many thanks to BIOEMTECH for hosting a terrific workshop and for inviting our CEO, PD Dr. Felix Gremse, to present the latest features of our ImalyticsPreclinical software. We look forward to a sustained collaboration with this innovative company, driving advancements in preclinical imaging.

💡 Spotlight: Dosimetry Tool 💡

We're excited to highlight one of the newer features of our ImalyticsPreclinical software – the Dosimetry Tool.
Dosimetry, the quantitative assessment of ionizing radiation dose absorbed by matter, is an important component in the development of radiopharmaceuticals for both diagnostic imaging and targeted radiotherapy. Our tool provides researchers with precise, voxel-based internal dose assessment tools, enabling our users to assess novel radiopharmaceutical toxicity, enhance insights pertaining to biodistribution, and improve comparative assessment.
Check out the publication of Dr. Carolyn Anderson and her team who have been utilizing our Dosimetry Tool to advance their groundbreaking research. They discovered that 89Zr- and 177Lu-L804-IAB2MA may be a promising theranostic pair for imaging and therapy of prostate cancer 🔬.

Platform Expo at RI-MUHC

Last week, we were excited to sponsor the Platform Expo at the Research Institute of the MUHC.
We were also thrilled to receive a tour of the Small Animal Imaging Lab (SAIL).
With our ImalyticsPreclinical software now installed at the MUHC SAIL, it was a fantastic opportunity to connect with researchers and users, and to learn more about their exciting ongoing projects.
We're looking forward to continuing to support the amazing work happening at McGill University!

WMIC Recap

Last week was an exciting one for Gremse-IT! We had the pleasure of:
- Attending the MILabs user meeting, where PD Dr. Felix Gremse gave a live demo of #ImalyticsPreclinical.
- Sponsoring the #radiotheranostics pre-meeting at WMIC (World Molecular Imaging Society), gaining valuable insights from top experts in the field.
- Connecting with many of our users at our booth and meeting talented researchers passionate about our software.
- Hosting a memorable 'Evening with Gremse-IT' at our new Montreal office.
Check out some highlights from the week here:

Invitation Gremse-IT (Montreal) 📜

To celebrate the opening of our new office in Montreal, we would like to welcome everyone to an "Evening with Gremse-IT" during the week of the WMIC, hosted by World Molecular Imaging Society.
When: Wednesday, September 11th at 8:00 PM EST
Where: Gremse-IT Downtown Montreal office (1275 Avenue des Canadiens-de-Montréal. Montreal, QC H3B 0G4)
We look forward to seeing you there!

💡 Spotlight: The Scribble Tool 💡

We are excited to highlight a feature of our Imalytics software, the Scribble Tool.
Given the importance of segmentation in any analysis workflow, we are on a mission to simplify this process for our users! While the most common method of isolating ROIs is a lengthy process of drawing slice by slice, the scribble tool enables an interactive method of delineating region boundaries in just a few slices. Once some “scribbles” are drawn in 2D, our software interpolates a 3D wireframe, and connects the region to form a class. The segmentation can also be adjusted incrementally, allowing Imalytics` users to perfect their analysis. Through a shallow learning approach, our software learns the segmentation from the user’s input. Here’s an example of the scribble tool in action, displayed on a CT of a mouse spleen.

Gremse-IT at WMIC 2024 in Montreal!

We are thrilled to announce that Gremse-IT will be attending the World Molecular Imaging Congress (WMIC) 2024 in Montreal held by the World Molecular Imaging Society!
Join us from September 9-13, 2024, at the Palais des Congrès de Montréal.
📍 Visit Us at Booth 211: Discover our innovative image analysis solutions and meet our team of experts.
🎉 Evening Event: We are hosting an evening social event on Wednesday, September 11th. More details to come!

Stay tuned for updates and see you in Montreal!

More than 260 Imalytics publications

The Imalytics Preclinical has already been used for more than 260 publications by authors from academia and industry! Thereby, the Imalytics Preclinical enabled the reproducible and reliable analysis of various imaging studies. We thank the scientists for their trust in us and in Imalytics Preclinical.

BIOEMTECH 2024 in Athens

🚀 Exciting News! Join us at the 4th Annual BIOEMTECH Preclinical Workshop in Athens, Greece! 🚀
🗓️ Dates: October 14-18, 2024 📍 Location: Athens, Greece
PD Dr. Felix Gremse, CEO of Gremse-IT, will be giving a talk on Dosimetry and leading an interactive hands-on course at this year's BIOEMTECH Preclinical Workshop. This event is a must-attend for anyone involved in the Drug and Radioligand Therapy field, offering a unique blend of networking and in-depth learning.
📢 Register now: https://bioemtech.com/training/4th-preclinical-models-imaging-workshop/
Let’s advance the future of drug discovery and targeted radioligand therapy together. See you in Athens!

Publication highlight 🔎📖

Very interesting research from our very own Diana Möckel! In this work, she demonstrated that inhibiting the CCL2-CCR2 pathway in a breast cancer mouse model induces vascular normalization and reduced the presence of harmful immune cells, therefore improving drug delivery and effectiveness.
The#imalytics was used to analyze three dimensional volume renderings from CT and Fluorescence data for qualitative and quantitative results across multiple time points.
Here are some elegant images from the paper; to read the full article, click here:

☀ Summer time at Gremse-IT ☀

On the 19th July 2024, Felix invited all of his colleagues from Gremse-IT GmbH to his home in Belgium. After a lovely walk through the narrow alleys, everyone enjoyed a traditional BBQ and cold drinks.

We wish everyone a nice summer!

New webpage!

We’re excited to unveil the brand-new webpage for Imalytics, our advanced and premium preclinical image analysis software!
Visit us to explore all the latest features and capabilities that make ImalyticsPreclinical the ultimate tool for researchers and professionals in preclinical imaging.

Our goal was to create a user-friendly browsing experience that is easy to navigate and provide visitors with a simple way to discover more information about our Imalytics software. We will be regularly updating our content with new and helpful information.

Gremse-IT Montreal update

Here’s an update on what Gremse-IT’s Montreal team has been working on!🏒 🍁

Since May, the software team has developed a deep learning model for automated bone tissue segmentation with some of our collaborators. We have also been working hard on our automated analysis of a wide variety of Phantech, LLC phantoms and some general AI applications in Imalytics, including an automated, atlas-based segmentation tool.

Our business development team has been attending conferences (#PIC and Society of Nuclear Medicine and Molecular Imaging (SNMMI)), working on the Gremse-IT brand, new applications and industries, as well as finding the best ways to bring hashtag#imalytics and our expertise in preclinical imaging to users worldwide!

Our Montreal team is specialized in tackling image analysis problems
requiring automation.

Reach out to info@gremse-it.com to collaborate!

IQ GLAMS summer school 2024

At the IQ GLAMS Summer School on "ADVANCED MOLECULAR IMAGING" (June 24-27), Felix Gremse gave three courses (60 minutes) on various data analysis with different modalities using our image analysis software Imalytics Preclinical: µCT, MRI, Optical, Ultrasound, MPI, PET, SPECT. The participants (25 PhD students and Post-Docs from different institutes) were given access to the Imalytics and worked with our tutorials themselves.

PhD position available (Milano)

📢 Exciting PhD Opportunity! 📢
Gremse-IT is collaborating with the University of Milano-Bicocca, Italy, to hire a PhD student for an innovative research project.
🔬 Project Title: "Development and application of image processing procedures for biological signal extraction and evaluation of regional functions and connectivity in an animal model of human disorders."
(https://www.unimib.it/sites/default/files/2024-06/STRATEGIC_DEF_AF.pdf)
This project aims to build an automatic software package for the calculation of brain function as well as its regional molecular network. If you're passionate about software development, image processing, and neuroscience, this is an incredible opportunity to contribute to groundbreaking research.
📍 Location: University of Milano-Bicocca, Milan, Italy
🔗 Apply Now: Application (Deadline: July 18th 2024)

SoftReach project

Together with some outstanding partners from academy (FORTH Institute of Molecular Biology & Biotechnology, the University of Thessaly, the University of Cyprus, and the King´s College London, Gremse-IT GmbH forms the consortium of the SoftReach Project. The aim of this innovative project is to revolutionize neurological disorder treatment with robotics. Find out more about this outstanding project!

Meet us at the PIC 2024

Would you like to learn more about combining reliable phantoms (Phantech, LLC) and their automated analysis using the Imalytics Preclinical software (Gremse-IT GmbH)? Or would you like to explore our new and innovative features such as the dosimetry tool and the brain atlas? Meet us at PIC2024 and improve your future preclinical imaging studies together with us!

Meet us in Dijon

Meet us at the second workshop of CGFL and MR Solutions on April 10th until April 12th at the Cancer Center Georges-Francois Leclerc (CGFL) in Dijon, France.

Meet us at EMIM 2024 in Porto

We look forward to seeing you at #EMIM 2024 in Porto.

Meet us at our booth 205 or come to our industry meeting!

Tech Exchange 2.2.2024 2:00 p.m. CET

PD Dr. Felix Gremse will present our image analysis software "Imalytics Preclinical" at the Tech Exchange of the Euro-BioImaging Industry Board.
Please join the webinar on Friday, February 2nd at 2:00 p.m. CET!

Merry christmas and happy new year 2024

Traditionally, our Gremse-IT GmbH Christmas party took place in Belgium. This year again in Liège. By climbing the famous stairs, trying not to fall on the ice, and having a delicious lunch, we celebrated many new colleagues, interesting projects, and the growth of the company.

Now, 2023 has only a few days left...
We wish you a festive season full of joy and warmth!
Looking forward to a fantastic start to a successful year 2024!

WMIC 2023 (Prague)

The CEO of our company, PD Dr. Gremse, has joined the Scintica booth at the WMIC 2023 in Prague, which confirms the opening of a new chapter in our bilateral collaboration. Productive talks with a breathtaking view over Prague city.

If you attended the WMIC 2023, please don't hesitate to contact us and explore the thrilling functionality of our super-friendly Imalytics Preclinical Software, which has already gained the sympathy of numerous molecular imaging experts around the world.

Don't be shy to learn how to deal with time-consuming analyzes in a few smart clicks!

MILabs User Meeting in Prague

Felix Gremse participated in the MILabs User Meeting (4th September 2023), which was organized on the 24th floor! New heights — new benchmarks. A top opportunity to expand scientific ties in the sphere of preclinical imaging.

Highly appreciate our long-standing cooperation with MILabs and such a wonderful chance to meet new scientists from all corners of the world.

Let's stay in touch!

Spring mood: PIC meeting in Michigan

Held in Mai at the Michigan State University, East Leasing, MI, the Preclinical Imaging Consortium (PIC) Conference brought together our CEO, PD Dr. Felix Gremse, Stephen Marchant (CEO and Founder of MediLumine Inc.), Zach Gurberg (Application Scientist at Gremse-IT GmbH) and Ryan Washer (Application Scientist at Gremse-IT GmbH). The conference has inspired them to push forward a new useful feature that has been successfully implemented into our software during the last months.

Thank you to all the participants for a valuable scientific experience and our team for a great job! Hope to see you soon, guys!

Mac OS and dark mode

In the last months, our developers have been working intensively on the Mac OS integration of our image analysis software Imalytics Preclinical. Already several customers are using our software on their MACs. If you are interested in testing the software, please send us an eMail to info@gremse-it.com. As part of this improvement process, we have also introduced dark mode, a preferred working mode.

Webinar 9th November 2022

Don't miss our first webinar on the 9th November (Wednesday) at noon EST with PD Dr. Felix Gremse and Zach Gurberg, organized by MediLumine.

Learn how you can drastically reduce the amount of time you spend on your PET/CT or SPECT/CT image analysis.

Register for the webinar here: https://lnkd.in/gTiXyxff

Meet us at: WMIC 2022 (Miami)

Felix Gremse and Stephen Marchant, CEO MediLumine, can't wait to see you at WMIC at Booth 305!

***Explanatory videos***

In the last weeks, we have recorded many explanatory videos to make learning of the Imalytics Preclinical software even easier. Each video has an information slide at the beginning that summarizes the content of the video. You can find the videos on our Imalytics Preclinical YouTube channel and also in the latest version of the software. Hope it helps!

Meet us at: Total-body PET

Felix Gremse will participate in the Total-body PET-2022 conference. It is jointly organised by the University of Edinburgh, Scotland and Ghent University, Belgium. It will take place (In-person): 24th to 26th September 2022 at the prestigious McEwan Hall, Edinburgh, Scotland. Come there and discuss with Felix some preclinical and clinical applications of total-body PET!

Meet us at: ToScA UK & Europe 2022

Gremse-IT GmbH will join the 13 th Tomography for Scientific Advancement (ToScA) symposium UK & Europe 2022 which will be held at the Queen Mary University in London, UK from 7th to 9th September 2022. This conference focuses on the broad and multidisciplinary range of tomography applications, but will also include themes in biological (hard and soft) tissue imaging, understanding materials in 3D, and recent advances in hardware and software tools. We look forward to fruitful discussions and networking with other scientists.

Video about Imalytics Preclinical

Here is a great and informative video about Imalytics Preclinical, recorded by Zach Gurberg, Application Scientist at Gremse-IT GmbH and MediLumine (distributor of Imalytics Preclinical in North America). He focuses on REAL-TIME 3D segmentation and quantification of bone, heart, kidneys, and urinary bladder using a dynamic PET-CT scan. Additionally, he also explains the benefits of the Azure Cloud.

Imalytics Preclinical version 3.0.1.3

New release: Imalytics Preclinical version 3.0.1.3 is ready for download!

If you are already a user of our Imalytics Preclinical software, you can get a new installer for our latest version 3.0.1.3. Please send us an eMail to support@gremse-it.com.

If you have not yet tried our innovative biomedical image analysis software Imalytics Preclinical, please send us an eMail to info@gremse-it.com.

Gremse-IT at the SNMMI Annual meeting

Gremse-IT GmbH had a pavilion at the SNMMI 2022 Annual Meeting June 11-14, 2022, in Vancouver, BC, Canada. Our CEO Felix Gremse and Zach Gurberg (application scientist, MediLumine) had a great time!

Thank you for all the fruitful discussions and scientific exchange.

Meet us at the EMIM 2022 in Thessaloniki

Finally, the EMIM will take place in Thessaloniki ( 15th – 18th March ). Our CEO, Felix Gremse, attended this meeting and it was just fantastic because of all the great researchers, the interesting industry partners, the many scientific education sessions (ES), talks, and poster presentations.

Meet us in January 2022

Gremse IT GmbH wanted to join the 35th International Austrian Winter Symposium that took place January 19-21, 2022 in Bad Ischl, Austria.

Unfortunately, we had to cancel but we hope that every attendee had a great symposium!

Imalytics Preclinical Version 3.0

After months of programming, version 3.0 of our image analysis software "Imalytics Preclinical" has finally been released in December 2021.

What is new?

• Revised and improved user interface (new icons, comprehensive and descriptive tool tips, reorganizing the structure of the tutorials)
• New 3D segmentation features (iso tool and scribbles)
• Undo/redo for all segmentation and image operations
• Fusion of 3D and 2D images, e.g. CT with bioluminescence